Molecular Design

One piece of general advice that I offer to fellow scientists is to not let the fact that an article has been published in Nature (or any ot...

I’ll be taking a look at B2023 (Fused Tetrahydroquinolines Are Interfering with Your Assay) in this post. The article has already been disc...

 << previous | I’ll wrap up (at least for now) the series of posts on chemical probes by returning to the use of cheminformatic model...

I’ll be discussing promiscuity in this post and, if there’s one thing that religious leaders and drug discovery scientists agree on, it’s th...

| next >> I’ll be taking a look at some of the criteria, specifically structural alerts, by which chemical probes are assessed and he...

I've been meaning to take a look at the Seven Year Itch (SYI) article on PAINS for some time. SYI looks back over the the preceding 7...