Molecular Design

Given that it was International Women's Day yesterday, I'll open the the post (and blogging for 2025) with a photo of a gravestone a...

<< Previous I examined an  article on the polarized nature of protein-ligand binding interfaces previously and promised that I...

So in this blog post, written specially for #RealTimeChem week on an #OldTimeChem theme, I'll start ten years after the Kaiser's gr...

<< Previous || Next >> In the previous post , I questioned the validity of scaled ligand efficiency metrics (LEMs) such as L...

Those of you who follow this blog will know that I have a long standing interest in alkane/water partition coefficient and I’d like to tel...

It's almost three months since I arrived in Brasil to spend year in São Carlos at Universidade de São Paulo. One of the advantages of b...

This post got prompted one by Dan at Practical Fragments and I'm going to ask you to first take a look at that and at the comments. Now...