Molecular Design

<< previous || next >> I am currently in Rapa Nui (aka Easter Island) and it seemed fitting to continue the series on compo...

<< previous || next >> I’m guessing that this may be the first blog post on screening library design to be written in Tierr...

|| next >> Tonight seemed like a good time to start the series of posts on screening library design. For those of you who don’t k...

|| next >> I’m looking forward to posting on design of compound libraries for fragment screening. However, before launching that seri...

previous || next >> Mel reviewed an important article on maximal affinity of ligands to kick off our sequence of posts on ligand ef...

previous || next >> I originally intended to discuss some of the factors that impose the upper limits on binding that are observed....

Fragments typically have to be screened at high concentration because they normally only bind weakly to their targets and the physicochemica...