Molecular Design

Controlling the behavior of compounds and materials by manipulation of molecular properties.

Thursday, 11 February 2010

Ligand protein interactions by SPR

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I have now been in Melbourne for about a month and have found the city very much to my taste. I’m visiting some friends to help out with so...
Tuesday, 3 November 2009

Screening libraries: Sampling Chemical Space

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<< previous || next >> I am currently in Rapa Nui (aka Easter Island) and it seemed fitting to continue the series on compo...
Saturday, 3 October 2009

Screening Libraries: Diversity & Coverage

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<< previous || next >> I’m guessing that this may be the first blog post on screening library design to be written in Tierr...
Wednesday, 22 July 2009

Screening Libraries: Introduction

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|| next >> Tonight seemed like a good time to start the series of posts on screening library design. For those of you who don’t k...
Sunday, 7 June 2009

Scaling potency by lipophilicity and molecular size

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|| next >> I’m looking forward to posting on design of compound libraries for fragment screening. However, before launching that seri...
Tuesday, 14 April 2009

The upper limits of binding: Part 2

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previous || next >> Mel reviewed an important article on maximal affinity of ligands to kick off our sequence of posts on ligand ef...
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Monday, 6 April 2009

The upper limits of binding: Part 1

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previous || next >> I originally intended to discuss some of the factors that impose the upper limits on binding that are observed....
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