Molecular Design

I must confess that I’ve never been a big fan of QSAR. When I started in Pharma 24 years ago, QSAR was seen as as something that would sol...

We often hear and read that pharmacological promiscuity is strongly correlated with lipophilicity and it's often a good idea to check th...

It's almost three months since I arrived in Brasil to spend year in São Carlos at Universidade de São Paulo. One of the advantages of b...

It’s not often that bloggers get responses from the authors of the articles that they’ve featured and it’s much rarer still for a re...

Getting the most from target-ligand interactions is the essence of structure-based design and many of us believe that fragment-based methods...

The editors of the Journal of Computer-Aided Molecular Design commissioned a number of Perspectives on the state and future of the field to...

FBDD is a maturing field and one sign this maturation is the publication of a volume of Methods in Enzymology devoted to the subject. The...