Molecular Design

Controlling the behavior of compounds and materials by manipulation of molecular properties.

Saturday, 13 September 2014

Saving Ligand Efficiency?

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<< Previous | I’ll be concluding the series of posts on ligand efficiency metrics (LEMs) here so it’s a good point at which to rem...
3 comments:
Thursday, 4 September 2014

Efficiency can also be lipophilic

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<< Previous || Next >> In the previous post , I questioned the validity of scaled ligand efficiency metrics (LEMs) such as L...
Saturday, 30 August 2014

Ligand efficiency metrics considered harmful

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Next >> It has been a while since I did a proper blog post. Some of you may have encountered a Perspective article entitled, ‘Ligan...
2 comments:
Wednesday, 4 June 2014

Ligand efficiency metric teaser

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Here's a bit of fun. See how these parallel lines transform when you divide Y by X (this is how you calculate ligand efficiency). ...
Friday, 23 August 2013

To review or not to review?

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I'll admit that I don’t always see eye-to-eye with journal editors although it has been a while since I last blogged on this theme . ...
1 comment:
Tuesday, 13 August 2013

Malan's Ten Rules for Air Fighting

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I'm going to introduce the #SavingPharma hashtag in this post but I'm also going to introduce WW2 fighter pilot (and apartheid oppo...
Sunday, 4 August 2013

Presentations on slideshare

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I recently uploaded some presentations to slideshare including my recent Gordon conference talk and the slide set used on visits to a co...
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