Molecular Design

I was in Kuala Lumpur about this time last year and visited International Medical University where I delivered a harangue .  It was a very...

| next >> So I promised do a blog post on rhodanines .  This isn’t really a post on rhodanines or even PAINS .  It’s act...

A new year and a new title for the blog which will now just be ‘Molecular Design’.  I have a number of reasons for dropping fragment-based...

<< Previous | I’ll be concluding the series of posts on ligand efficiency metrics (LEMs) here so it’s a good point at which to rem...

<< Previous || Next >> In the previous post , I questioned the validity of scaled ligand efficiency metrics (LEMs) such as L...

Next >> It has been a while since I did a proper blog post. Some of you may have encountered a Perspective article entitled, ‘Ligan...

Here's a bit of fun. See how these parallel lines transform when you divide Y by X (this is how you calculate ligand efficiency). ...