Sunday, 31 December 2023

Chemical con artists foil drug discovery

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One piece of general advice that I offer to fellow scientists is to not let the fact that an article has been published in Nature (or any ot...
Tuesday, 19 December 2023

On quality criteria for covalent and degrader probes

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I’ll be taking a look at H2023 (Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes) in this post and this ar...
Wednesday, 6 December 2023

Are fused tetrahydroquinolines interfering with your assay?

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I’ll be taking a look at B2023 (Fused Tetrahydroquinolines Are Interfering with Your Assay) in this post. The article has already been disc...
2 comments:
Sunday, 19 November 2023

On the misuse of chemical probes

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It’s now time to get back to chemical probes and I’ll be taking a look at S2023 (Systematic literature review reveals suboptimal use of che...
3 comments:
Wednesday, 27 September 2023

Five days in Vermont

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A couple of months ago I enjoyed a visit to the US (my first for eight years) on which I caught up with old friends before and after a few d...
Wednesday, 26 July 2023

Blogger Meets Blogger

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Over the years I’ve had had some cool random encounters (some years ago I bumped into a fellow member of the Macclesfield diving club in the...
Tuesday, 18 July 2023

AI-based drug design?

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|| >> Next I’ll start this post by stressing that I’m certainly not anti-AI. I actually believe that drug design tools that are being ...
1 comment: