Molecular Design

Controlling the behavior of compounds and materials by manipulation of molecular properties.

Wednesday, 27 March 2024

Leadeth me unto Truth and delivereth me from those who have already found it

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A theory has only the alternative of being true or false. A model has a third possibility: it may be true, but irrelevant. With apologies to...
Sunday, 31 December 2023

Chemical con artists foil drug discovery

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One piece of general advice that I offer to fellow scientists is to not let the fact that an article has been published in Nature (or any ot...
Tuesday, 19 December 2023

On quality criteria for covalent and degrader probes

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I’ll be taking a look at H2023 (Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes) in this post and this ar...
Wednesday, 6 December 2023

Are fused tetrahydroquinolines interfering with your assay?

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I’ll be taking a look at B2023 (Fused Tetrahydroquinolines Are Interfering with Your Assay) in this post. The article has already been disc...
2 comments:
Sunday, 19 November 2023

On the misuse of chemical probes

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It’s now time to get back to chemical probes and I’ll be taking a look at S2023 (Systematic literature review reveals suboptimal use of che...
3 comments:
Wednesday, 27 September 2023

Five days in Vermont

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A couple of months ago I enjoyed a visit to the US (my first for eight years) on which I caught up with old friends before and after a few d...
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