Molecular Design

Controlling the behavior of compounds and materials by manipulation of molecular properties.

Tuesday, 30 July 2024

A Nobel for property-based drug design?

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[This post was updated on 10-Aug-2025 to mention my review of CNM2025 (Return to Flatland) which  critically examines ( 35 ) (Escape from ...
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Monday, 20 May 2024

A time and place for Nature in drug discovery?

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I’ll be reviewing Y2022 (The Time and Place for Nature in Drug Discovery) in this post and stating my position on natural products in moder...
Monday, 1 April 2024

Standard states and solution thermodynamics

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<< previous || next >> Readers of this blog know that, on more than one occasion, I have denounced the ligand efficiency metri...
Wednesday, 27 March 2024

Leadeth me unto Truth and delivereth me from those who have already found it

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A theory has only the alternative of being true or false. A model has a third possibility: it may be true, but irrelevant. With apologies to...
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